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Ketamine Infusion Therapy for Depression
R & R MD treats even the most aggressive cases of depression
Ketamine has been used to treat depression for viable candidates since the early 2000s when medical professionals noticed its ability to rapidly alleviate depression and suicidal thoughts. Scientists and medical physicians have sung its praises for producing effective results as an alternative to common antidepressants and mood-enhancing medications. Not only has it been found to avoid the typical side effects experienced by antidepressant users, but it also produces faster and more consistent results, and in some cases, completely cures depression at its source.
How ketamine treats depression
Glutamate, an excitatory neurotransmitter in the brain, regulates large regions of our central nervous system. Glutamate is thought to play a key role in the development of depression. Stress and other factors can alter glutamate signaling in the brain and alter neurons to make them less resilient and less able to communicate with other neurons. Ketamine alters glutamate transmission which is thought to contribute to its ability to alleviate depression.
Ketamine infusions at Brookfield’s Reset Restore MD alter neurotransmitter receptors and pathways, triggering the rapid growth of new healthy neurological connections. Ketamine therapy has also been shown to treat symptoms of PTSD, chronic pain and addiction.
What is Depression?
Depression is a mental health disorder caused by a variety of factors like genetic predisposition, chemical imbalances in the brain, environmental stressors and life events such as trauma or loss. Symptoms vary based on the type of depression and the individual.
Common Depression Diagnoses
The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) recognizes several types of depression. Common types of depression include:
- Major Depressive Disorder (MDD): MDD is characterized by a persistent feeling of sadness or loss of interest in activities that a person used to enjoy. Other symptoms of MDD may include changes in appetite, sleep disturbances, fatigue, difficulty concentrating and thoughts of self-harm or suicide.
- Persistent Depressive Disorder (PDD): PDD, also known as dysthymia, involves chronic and persistent symptoms of depression lasting for at least 2 years in adults or 1 year in children.
- Postpartum Depression (PPD): PPD is a type of depression occurring after giving birth and is characterized by feelings of sadness, anxiety, or hopelessness, changes in appetite or sleep patterns and difficulty bonding with the baby.
- Seasonal Affective Disorder (SAD): SAD is a type of depression that typically occurs during the winter months when there is less natural sunlight. Symptoms can include fatigue, weight gain and difficulty sleeping.
- Bipolar Disorder: Bipolar disorder is a mood disorder that involves episodes of both depression and mania or hypomania, which can include symptoms like increased energy, racing thoughts and impulsive behavior.
Your medical team at Reset Restore MD will use the screening tool PHQ-9 to assess for the presence and severity of depression. The Patient Health Questionnaire (PHQ) scores each of the 9 DSM-V criteria for depression. This 9-item scale will be used before and upon completion of IV ketamine treatment.
Depression and Suicide
Those with depression may experience suicidality. The American Psychological Association defines suicidality as “the risk of suicide, usually indicated by suicidal ideation or intent, especially as evident in the presence of a well-elaborated suicidal plan.” It can also be defined to include suicidal thoughts, plans, gestures, or attempts. In 2021, suicide was the 2nd leading cause of death for people ages 20-34.
A 2023 systematic review, concluded ketamine treatment resulted in a significant reduction of suicidal ideation. Additionally, the systematic review demonstrated the superiority to IV ketamine versus intranasal. Full suicidal remission was reached in 30-60% of cases. Ketamine and esketamine in suicidal thoughts and behaviors: a systematic review - PMC (nih.gov)
If you or someone you love are experiencing active suicidal ideations please seek emergent medical attention, call 911 or call 988.
Real Feelings. Real Reviews.
"Reset Restore was an out of the blue experiment for myself to truly test if anything could even dent my depression. The treatment plan was low dosage Ketamine for a medium duration - a little less than an hour. We scheduled six treatments. Progress started day one. My depression has plagued me for almost eight years. Everyone has a different experience for their depression(s) but mine was deadly. I tried anti-depressants (two years on and quit), natural supplements, yoga, meditating, even jumping to energy drinks to alleviate the depressive symptoms, but nothing worked. The energy drinks made things worse but made me feel “sorta normal” but it was just not working. After the first treatment, I sh*t you not, something finally worked. The Ketamine did a deep scrub and pulled out whatever heavy fog had been gripping my brain for years. It helped me break my caffeine addiction. I felt energy, I felt better, I felt zero anxiety, I felt zero fatigue, I felt zero depression. That was literally after day one. From just a couple sessions my body felt relieved of a weight holding me down daily. The staff at Reset Restore are friendly and professional! If you have concerns or questions they fill you in on everything. I'm glad I met them! I'm glad I gave this a chance."
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Patients who use ketamine to treat depression
Patients most eligible for ketamine infusions are those who have tried a multitude of other treatments and medications with little to no improvement of their condition. If this sounds like you then you may be an ideal candidate for ketamine infusion therapy.
The experienced staff at R and R MD will dive deep into your medical, social, and emotional history to ensure we offer the best treatment options for you.